Michelle Pisani

PhD Student

Telephone: +61 2 6268 9522
Fax: +61 2 6268 8017
Email: m.pisani@student.adfa.edu.au
Location: PEMS Nth, Room 210

Field of Study - Biological Chemistry

Supervisor: Assoc. Prof. Grant Collins
Co-Supervisor: Dr Anthony Day

Research Topic - The Development of dinuclear Ruthenium (II) complexes as DNA and RNA binding anticancer drugs

Dinuclear ruthenium (II) complexes preferentially bind non-duplex DNA and RNA sites. Consequently, these compounds have significant potential as therapeutic agents. In this study the binding of the dinuclear ruthenium complexes to DNA/RNA and various drug delivery agents (dendrimers and cucurbiturils) is being examined.